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Health & Medicine
Vital Signs

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Vital Signs
   The Healing Power of Stories
   Herbal Supplements Can Interfere with HIV/AIDS Meds ... and
   Who Can Predict the Staying Power of Your Relationship?

With anthrax in the news these days, it seemed like a good idea to provide some info on anthrax that might not be the stuff making the headlines.  ...  

  • The Healing Power of Stories.
    The holiday season is a time of, among other things, stories.  And cultural traditions have recognized for a long time the importance of stories to health and well-being.  But increasingly, the healing power of stories has been coming to the attention of the medical community.
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    One example is a recent review of a book entitled Tell Me a Story: The Life-Shaping Power of Our Stories by Daniel Taylor [Bog Walk Press, 2001] in MedScape's on-line General Medicine Journal [free reg. required].  Evidently, Taylor, who is a Professor of English Literature at Bethel College in St. Paul, Minnesota, came to the attention of reviewer, Dr. Beverly Steinman, of the Northwest Center for Physician-Patient Communication, at an earlier Annenberg conference on patient safety. 
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    While Dr. Steinman acknowledges that Taylor's Tell Me a Story is not written specifically for the medical community, she says its "the type of book that can expand horizons so that health professionals may go beyond the usual approach to patients."  She also goes on to emphasize in particular the sixth chapter, "Healing Broken Stories," which, according to Steinman, "illustrates strongly how stories can play a role in the practice of medicine."  She goes on to note that "sharing stories -- especially those of brokenness -- can lead to a connection between healer and patient that empowers the therapeutic relationship beyond its usual confines."
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  • Herbal Supplements Can Interfere with HIV/AIDS Meds
    Researchers at the National Institute of Allergy and Infectious Diseases [NAAID] have reported that garlic supplements -- which many ordinarily think of as a helpful supplement with a variety of uses, including fighting infections and lowering cholesterol and blood pressure -- were found to reduce the efficacy of saquinavir, a protease inhibitor commonly used as part of cocktail regimens in the treatment of HIV/AIDS.
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    In a sample of healthy test participants, three weeks of daily intake of garlic supplements were shown to reduce serum blood levels of saquinavir by more than 50%.  And even after the participants stopped taking the supplements and were re-tested 10 days later, blood levels were still 35% below what would have been expected.  According to a Doctor's Guide report, senior co-author Judith Falloon, M.D., an AIDS clinical researcher at NAAID said, "We saw a definite, prolonged interaction.  The clear implication is that doctors and patients should be cautious about using garlic supplements during HIV therapy."
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    The garlic supplement study was the second by the team of researchers, who had earlier found that the common herbal remedy St. John's Wort exhibited a potentially dangerous interaction when used with the protease inhibitor indinavir.  They turned their attention next to garlic because, since many HIV/AIDS treatment regimens often result in increased cholesterol levels, the cholesterol-inhibiting properties associated with garlic had made it a popular supplement among those being treated for HIV/AIDS.  The researchers are not sure about precisely why garlic supplements causes the reduction in blood levels of saquinavir.  They do know that both garlic and protease inhibitors share the same pathway into the body -- the CYP450 enzyme system, a metabolic route.  But how garlic supplements actually disrupt the uptake of saquinavir is still not clear.
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  • Who Can Predict the Staying Power of Your Relationship?
    Stability and longevity in a relationship isn't always synonymous with good health, but it is usually a pretty good barometer of some things.  But will your relationship or marriage last?  ...
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    In order to answer that question, Dr. Christopher R. Agnew of Purdue University and some colleagues undertook a study to see whether or not "outsiders" can have any real insight into a relationship and its staying power.  According to Agnew, as Reuters' Health recently reported, despite assumptions to the contrary "friends can possess a great deal of prognostic information concerning our involvements."
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    Agnew & Co. studied 74 male-female couples and their friends, including mutual friends and friends of either individual of the couple.  All participants, including the couple, were then asked to rate the couple on things like commitment and closeness. The results?  The women's friends were best at predicting the fate of the relationship 6 months down the road.  Men were least likely to be accurate in that regard, and the mutual friends of both partners of a couple were almost as likely as the woman's friends to be accurate.  But even more interesting, perhaps, the ability of the women's friends to predict a couple's future remained significantly accurate "even when the couple members' own perceptions were taken into consideration."  The findings appear in the December issue of the Journal of Personality and Social Psychology.

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